- Tokyo University of Pharmacy and Life Science
TGF-β is a multipotent cytokine, acting throughout development and adulthood in whole body. My focus is on the TGF- superfamily members and how their downstream transcription factors regulate target genes that are important for development and maintenance of blood vascular and lymphatic vessels. ECs behaviors are very much different between in vivo and in vitro situations, so I use genetically modified mice to evolve the techniques used to future clinical applications such as translational research, regenerative medicine.
|Sep. 9 (Wed)
Angiogenesis and Vascular Remodeling
||(Short Talk) Depletion of Endothelial TGF-β Signaling Induces Tumor Angiogenesis and Metastasis