- Max Planck Institute for Heart and Lung Research
Didier’s work is widely credited for pioneering the use of the zebrafish system to study the development and function of multiple organ systems including the heart, pancreas and liver. His lab investigates questions in cell differentiation, tissue morphogenesis, organ homeostasis and function, as well as organ regeneration. It studies these questions in zebrafish as well as in mouse and is currently looking at several mesodermal (heart, vasculature) and endodermal (pancreas, lung) organs. The lab utilizes both forward and reverse genetic approaches, and aims to dissect cellular processes using high-resolution live imaging. One of the goals is to gain understanding of vertebrate organ development at the single-cell level. In the past several years, Didier’s lab has also become interested in issues pertaining to genetic compensation and transcriptional adaptation.
|Sep. 9 (Wed)
Specification and Differentiation of Endothelial Lineage
||Biological Robustness: Genetic Compensation and Transcriptional Adaptation